You want the first oil changed right away, that's why the manual says 50 hours. When an engine is new and it gets heated up for the first time any assembly greases, sealants, casting material and gasket fragments on the new engine parts will come off and get carried away in the oil. Also there will be metal shavings as the new parts wear in together.
I do a first oil and filter change on any new car, truck or motorcycle after driving it around for one day, so always 100 miles or less. I got a new 2022 KLR 650 last September and I rode it for one nice afternoon and changed the oil and filter as soon as I got it home. I have 468 miles on it now and it will go in for it's first service at 600 miles.